BT2, CAS [[34576-94-8]]

Produktübersicht

• Artikelname: BT2, CAS [[34576-94-8]]
• Artikelnummer: FBM-10-4717
• Hersteller Artikelnummer: 10-4717
• Alternativnummer: FBM-10-4717-10MG, FBM-10-4717-50MG
• Hersteller: Focus Biomolecules
• Kategorie: Biochemikalien
• Alternative Synonym: Chemical Name: 3,6-Dichlorobenzo[b]thiophene-2-carboxylic acid

Produktbeschreibung

BCKDC kinase inhibitor

Produkteigenschaften

• Molekulargewicht: 247.10
• Reinheit: 95% by TLC NMR (Conforms)
• Formulierung: Off-white solid
• CAS Nummer: [34576-94-8]
• Formel: C9H4Cl2O2S

Anwendungsbeschreibung

• Anwendungsbeschreibung: BT2 is an inhibitor of the mitochondrial branched-chain alpha-ketoacid dehydrogenase complex kinase (BCKDC) - IC50 = 3.19 µM.1 Inhibition of this kinase has been shown to reduce levels of branched-chain amino acid concentrations in vivo. BT2 has also been shown to be a moderate inhibitor (Ki = 59 µM) of myeloid cell leukemia 1(Mcl 1), a Bcl-2 family protein.2