BT2, CAS [[34576-94-8]]

Product Overview

• Article Name: BT2, CAS [[34576-94-8]]
• Biozol Catalog Number: FBM-10-4717
• Supplier Catalog Number: 10-4717
• Alternative Catalog Number: FBM-10-4717-10MG, FBM-10-4717-50MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: Chemical Name: 3,6-Dichlorobenzo[b]thiophene-2-carboxylic acid

Product Description

BCKDC kinase inhibitor

Product Properties

• Molecular Weight: 247.10
• Purity: 95% by TLC NMR (Conforms)
• Form: Off-white solid
• CAS Number: [34576-94-8]
• Formula: C9H4Cl2O2S

Application Notes

• Application Notes: BT2 is an inhibitor of the mitochondrial branched-chain alpha-ketoacid dehydrogenase complex kinase (BCKDC) - IC50 = 3.19 µM.1 Inhibition of this kinase has been shown to reduce levels of branched-chain amino acid concentrations in vivo. BT2 has also been shown to be a moderate inhibitor (Ki = 59 µM) of myeloid cell leukemia 1(Mcl 1), a Bcl-2 family protein.2