(R)-(+)Etomoxir Na, CAS [[828934-41-4]]

Produktübersicht

• Artikelname: (R)-(+)Etomoxir Na, CAS [[828934-41-4]]
• Artikelnummer: FBM-10-4731
• Hersteller Artikelnummer: 10-4731
• Alternativnummer: FBM-10-4731-5MG,FBM-10-4731-25MG,FBM-10-4731-10MM/1MLDMSO
• Hersteller: Focus Biomolecules
• Kategorie: Biochemikalien

Produktbeschreibung

Carnitine palmitoyltransferase inhibitor

Produkteigenschaften

• Molekulargewicht: 320.74
• Reinheit: 98% by HPLC, NMR (Conforms)
• Formulierung: White solid
• CAS Nummer: [828934-41-4]
• Formel: C15H18ClO4Na

Anwendungsbeschreibung

• Anwendungsbeschreibung: Etomoxir (828934-41-4) is an irreversible inhibitor of mitochondrial carnitine palmitoyl transferase 1 (CPT1).1 It is widely used to study fatty acid oxidation. Etomoxir has been investigated as a therapeutic agent for heart disease2, diabetes3, and cancer4,5. Use of etomoxir in concentrations greater than 5 µM induces acute production of ROS with associated evidence of severe oxidative stress in proliferating T cells indicating a loss of specificity for CTP1 at these concentrations.6 200 µM etomoxir inhibited complex I of the electron transport chain.7