(R)-(+)Etomoxir Na, CAS [[828934-41-4]]

Product Overview

• Article Name: (R)-(+)Etomoxir Na, CAS [[828934-41-4]]
• Biozol Catalog Number: FBM-10-4731
• Supplier Catalog Number: 10-4731
• Alternative Catalog Number: FBM-10-4731-5MG, FBM-10-4731-25MG, FBM-10-4731-10MM/1MLDMSO
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: Chemical Name: (R)-(+)-2-[6-(4-Chlorophenoxy)hexyl]-oxirane-2-carboxylic acid sodium salt

Product Description

Carnitine palmitoyltransferase inhibitor

Product Properties

• Molecular Weight: 320.74
• Purity: 98% by HPLC, NMR (Conforms)
• Form: White solid
• CAS Number: [828934-41-4]
• Formula: C15H18ClO4Na

Application Notes

• Application Notes: Etomoxir (828934-41-4) is an irreversible inhibitor of mitochondrial carnitine palmitoyl transferase 1 (CPT1).1 It is widely used to study fatty acid oxidation. Etomoxir has been investigated as a therapeutic agent for heart disease2, diabetes3, and cancer4,5. Use of etomoxir in concentrations greater than 5 µM induces acute production of ROS with associated evidence of severe oxidative stress in proliferating T cells indicating a loss of specificity for CTP1 at these concentrations.6 200 µM etomoxir inhibited complex I of the electron transport chain.7