UK-5099, CAS [[56396-35-1]]

Produktübersicht

• Artikelname: UK-5099, CAS [[56396-35-1]]
• Artikelnummer: FBM-10-4748
• Hersteller Artikelnummer: 10-4748
• Alternativnummer: FBM-10-4748-5MG, FBM-10-4748-25MG
• Hersteller: Focus Biomolecules
• Kategorie: Biochemikalien
• Alternative Synonym: Chemical Name: 2-Cyano-3-(1-phenyl-1H-indol-3-yl)-2-propenoic acid

Produktbeschreibung

Mitochondrial pyruvate transporter inhibitor

Produkteigenschaften

• Molekulargewicht: 288.30
• Reinheit: 98% by TLC NMR (Conforms)
• Formulierung: Yellow solid
• CAS Nummer: [56396-35-1]
• Formel: C18H12N2O2

Anwendungsbeschreibung

• Anwendungsbeschreibung: Potent inhibitor of the mitochondrial pyruvate carrier (MPC).1 Rapidly increases glucose uptake in human monocytes.2 Attenuates mitochondrial oxidative phosphorylation and increases glycolysis creating greater stem-like properties in LnCap prostate cancer cells.3 Blocks the neuroprotective action of L-lactate or pyruvate during glutamate-induced excitotoxicity.4 Inhibits pyruvate transport across the plasma membrane of trypanosomes (Ki=49 µM).5