Ipatasertib, CAS [[1001264-89-6]]

Produktübersicht

• Artikelname: Ipatasertib, CAS [[1001264-89-6]]
• Artikelnummer: FBM-10-4751
• Hersteller Artikelnummer: 10-4751
• Alternativnummer: FBM-10-4751-5MG,FBM-10-4751-25MG
• Hersteller: Focus Biomolecules
• Kategorie: Biochemikalien
• Alternative Synonym: GDC-0068, RG7440

Produktbeschreibung

Pan-AKT inhibitor

Produkteigenschaften

• Molekulargewicht: 458.00
• Reinheit: 98% by HPLC NMR (Conforms)
• Formulierung: Off-white of pale pink solid
• CAS Nummer: [1001264-89-6]
• Formel: C24H32ClN5O2

Anwendungsbeschreibung

• Anwendungsbeschreibung: Ipatasertib is a selective (against a panel of 230 kinases) and potent pan-Akt inhibitor (IC50s: Akt1 = 5 nM, Akt2 = 18 nM, Akt3 = 8 nM).1 It displayed efficacy in xenograft models of prostate, breast, ovarian, colorectal, non-small cell lung, glioblastoma, and melanoma cancers.2 In clinical trials.