Ipatasertib, CAS [[1001264-89-6]]

Product Overview

• Article Name: Ipatasertib, CAS [[1001264-89-6]]
• Biozol Catalog Number: FBM-10-4751
• Supplier Catalog Number: 10-4751
• Alternative Catalog Number: FBM-10-4751-5MG,FBM-10-4751-25MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: GDC-0068, RG7440

Product Description

Pan-AKT inhibitor

Product Properties

• Molecular Weight: 458.00
• Purity: 98% by HPLC NMR (Conforms)
• Form: Off-white of pale pink solid
• CAS Number: [1001264-89-6]
• Formula: C24H32ClN5O2

Application Notes

• Application Notes: Ipatasertib is a selective (against a panel of 230 kinases) and potent pan-Akt inhibitor (IC50s: Akt1 = 5 nM, Akt2 = 18 nM, Akt3 = 8 nM).1 It displayed efficacy in xenograft models of prostate, breast, ovarian, colorectal, non-small cell lung, glioblastoma, and melanoma cancers.2 In clinical trials.