Binimetinib, CAS [[606143-89-9]]

Produktübersicht

• Artikelname: Binimetinib, CAS [[606143-89-9]]
• Artikelnummer: FBM-10-4789
• Hersteller Artikelnummer: 10-4789
• Alternativnummer: FBM-10-4789-5MG, FBM-10-4789-25MG
• Hersteller: Focus Biomolecules
• Kategorie: Biochemikalien
• Alternative Synonym: Chemical Name: 6-(4-Bromo-2-fluoroanilino)-7-fluoro-N-(2-hydroxyethoxy)-3-methylbenzimidazole-5-carboxamide. Alternate Names: ARRY-162, MEK162

Produktbeschreibung

MEK1/2 inhibitor

Produkteigenschaften

• Molekulargewicht: 441.23
• Reinheit: 99% by HPLC NMR (Conforms)
• Formulierung: White solid
• CAS Nummer: [606143-89-9]
• Formel: C17H15BrF2N4O3

Anwendungsbeschreibung

• Anwendungsbeschreibung: Binimetinib (606143-89-9) is a potent (IC50 = 12 nM) and selective allosteric inhibitor of MEK1/2.1,2 Recently approved by the FDA for treatment of melanoma in combination with Encorafenib. Binimetinib has had limited success as monotherapy but has shown promise in combination with other chemotherapeutic agents.3-5