Binimetinib, CAS [[606143-89-9]]

Product Overview

• Article Name: Binimetinib, CAS [[606143-89-9]]
• Biozol Catalog Number: FBM-10-4789
• Supplier Catalog Number: 10-4789
• Alternative Catalog Number: FBM-10-4789-5MG, FBM-10-4789-25MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: Chemical Name: 6-(4-Bromo-2-fluoroanilino)-7-fluoro-N-(2-hydroxyethoxy)-3-methylbenzimidazole-5-carboxamide. Alternate Names: ARRY-162, MEK162

Product Description

MEK1/2 inhibitor

Product Properties

• Molecular Weight: 441.23
• Purity: 99% by HPLC NMR (Conforms)
• Form: White solid
• CAS Number: [606143-89-9]
• Formula: C17H15BrF2N4O3

Application Notes

• Application Notes: Binimetinib (606143-89-9) is a potent (IC50 = 12 nM) and selective allosteric inhibitor of MEK1/2.1,2 Recently approved by the FDA for treatment of melanoma in combination with Encorafenib. Binimetinib has had limited success as monotherapy but has shown promise in combination with other chemotherapeutic agents.3-5