AZD1152-HQPA, CAS [[722544-51-6]]

Produktübersicht

• Artikelname: AZD1152-HQPA, CAS [[722544-51-6]]
• Artikelnummer: FBM-10-4804
• Hersteller Artikelnummer: 10-4804
• Alternativnummer: FBM-10-4804-5MG, FBM-10-4804-25MG
• Hersteller: Focus Biomolecules
• Kategorie: Biochemikalien
• Alternative Synonym: Chemical Name: 3-[[7-[3-[Ethyl(2-hydroxyethyl)amino]propoxy]-4-quinazolinyl]amino-N-(3-fluorophenyl)-1H-pyrazole-5-acetamide. Alternate Names: Barasertib-HQPA, AZD2811

Produktbeschreibung

Aurora B kinase inhibitor

Produkteigenschaften

• Molekulargewicht: 507.56
• Reinheit: 98% by HPLC NMR (Conforms)
• Formulierung: Yellow solid
• CAS Nummer: [722544-51-6]
• Formel: C26H30FN7O3

Anwendungsbeschreibung

• Anwendungsbeschreibung: AZD1152-HQPA is a potent and highly selective inhibitor of Aurora B.1 Aurora B Ki = 0.36 nM, Aurora A Ki = 1,369 nM.2 It inhibits the growth of tumors in multiple cancer models.3-6 Excessive ROS generation7 and upregulated tumor suppressor miRNAs8 have been proposed as a novel mechanisms of cytotoxicity of AZD1152-HQPA.