AZD1152-HQPA, CAS [[722544-51-6]]

Product Overview

• Article Name: AZD1152-HQPA, CAS [[722544-51-6]]
• Biozol Catalog Number: FBM-10-4804
• Supplier Catalog Number: 10-4804
• Alternative Catalog Number: FBM-10-4804-5MG, FBM-10-4804-25MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: Chemical Name: 3-[[7-[3-[Ethyl(2-hydroxyethyl)amino]propoxy]-4-quinazolinyl]amino-N-(3-fluorophenyl)-1H-pyrazole-5-acetamide. Alternate Names: Barasertib-HQPA, AZD2811

Product Description

Aurora B kinase inhibitor

Product Properties

• Molecular Weight: 507.56
• Purity: 98% by HPLC NMR (Conforms)
• Form: Yellow solid
• CAS Number: [722544-51-6]
• Formula: C26H30FN7O3

Application Notes

• Application Notes: AZD1152-HQPA is a potent and highly selective inhibitor of Aurora B.1 Aurora B Ki = 0.36 nM, Aurora A Ki = 1,369 nM.2 It inhibits the growth of tumors in multiple cancer models.3-6 Excessive ROS generation7 and upregulated tumor suppressor miRNAs8 have been proposed as a novel mechanisms of cytotoxicity of AZD1152-HQPA.