Necrosulfonamide, CAS [[1360614-48-7]]

Produktübersicht

• Artikelname: Necrosulfonamide, CAS [[1360614-48-7]]
• Artikelnummer: FBM-10-4860
• Hersteller Artikelnummer: 10-4860
• Alternativnummer: FBM-10-4860-5MG, FBM-10-4860-25MG
• Hersteller: Focus Biomolecules
• Kategorie: Biochemikalien
• Alternative Synonym: Chemical Name: (2E)-N-[4-[[(3-Methoxy-2-pyrazinyl)amino]sulfonyl]phenyl]-3-(5-nitro-2-thienyl)-2-propenamide

Produktbeschreibung

Necroptosis inhibitor / MLKL inhibitor

Produkteigenschaften

• Molekulargewicht: 461.47
• Reinheit: 98% by HPLC NMR (Conforms)
• Formulierung: Yellow solid
• CAS Nummer: [1360614-48-7]
• Formel: C18H15N5O6S2

Anwendungsbeschreibung

• Anwendungsbeschreibung: Specifically blocks necroptosis downstream of RIP3 activation by preventing MLKL-RIP3 interaction.1 Displays neuroprotective effects after ischemic brain injury.2 Prevents cystine-starvation-induced necroptosis and ferroptosis in human triple negative breast cancer cells.3 Binds to gasdermin D inhibiting pyroptosis and associated inflammatory cell death and sepsis.4 Rescues cells from TLR3 ligand-induced death.5