Chemical Name: 1-[(E)-(5-Methoxy-1H-indol-3-yl)methylideneamino]-2-pentylguanidine maleate. Alternate Names: SDZ HTF 919
5-HT4 partial agonist
Molekulargewicht:
417.47
Reinheit:
>98% by HPLC NMR (Conforms)
Formulierung:
Pale yellow solid
CAS Nummer:
[189188-57-6]
Formel:
C16H23N5OC4H4O4
Anwendungsbeschreibung:
Tegaserod is a potent and selective partial agonist of the serotonin 5-HT4 receptor.1,2 Tegaserod is an inhibitor of the RNA m6A reader YTHDF1.3 It reduced the viability of patient-derived AML cells and prolonged survival in xenograft models. Tegaserod also suppressed tumor growth in various models via inhibition of sonic hedgehog signaling4, MEK1/25, peroxisome pathway6, and others7.
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