UCPH-101, CAS [[1118460-77-7]]

Produktübersicht

• Artikelname: UCPH-101, CAS [[1118460-77-7]]
• Artikelnummer: FBM-10-4880
• Hersteller Artikelnummer: 10-4880
• Alternativnummer: FBM-10-4880-5MG, FBM-10-4880-25MG
• Hersteller: Focus Biomolecules
• Kategorie: Biochemikalien
• Alternative Synonym: Chemical Name: 2-Amino-4-(4-methoxyphenyl)-7-naphthalen-1-yl-5-oxo-4,6,7,8-tetrahydrochromene-3-carbonitrile

Produktbeschreibung

EAAT1 inhibitor

Produkteigenschaften

• Molekulargewicht: 422.48
• Reinheit: 98% by HPLC NMR (Conforms)
• Formulierung: Off-white solid
• CAS Nummer: [1118460-77-7]
• Formel: C27H22N2O3

Anwendungsbeschreibung

• Anwendungsbeschreibung: UCPH-101 is a potent (IC50 = 660 nM) and selective inhibitor of the excitatory amino acid transporter 1 (EAAT1).1,2 It induced cell death in glioblastoma cells via intracellular glutamate accumulation. UCPH-101 also significantly increased survival in glioma-bearing mice.3