UCPH-101, CAS [[1118460-77-7]]

Product Overview

• Article Name: UCPH-101, CAS [[1118460-77-7]]
• Biozol Catalog Number: FBM-10-4880
• Supplier Catalog Number: 10-4880
• Alternative Catalog Number: FBM-10-4880-5MG, FBM-10-4880-25MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: Chemical Name: 2-Amino-4-(4-methoxyphenyl)-7-naphthalen-1-yl-5-oxo-4,6,7,8-tetrahydrochromene-3-carbonitrile

Product Description

EAAT1 inhibitor

Product Properties

• Molecular Weight: 422.48
• Purity: 98% by HPLC NMR (Conforms)
• Form: Off-white solid
• CAS Number: [1118460-77-7]
• Formula: C27H22N2O3

Application Notes

• Application Notes: UCPH-101 is a potent (IC50 = 660 nM) and selective inhibitor of the excitatory amino acid transporter 1 (EAAT1).1,2 It induced cell death in glioblastoma cells via intracellular glutamate accumulation. UCPH-101 also significantly increased survival in glioma-bearing mice.3