DC-Y13-27, CAS [[3069691-93-6]]

Artikelnummer: FBM-10-4884
Artikelname: DC-Y13-27, CAS [[3069691-93-6]]
Artikelnummer: FBM-10-4884
Hersteller Artikelnummer: 10-4884
Alternativnummer: FBM-10-4884-5MG,FBM-10-4884-25MG
Hersteller: Focus Biomolecules
Kategorie: Biochemikalien
Alternative Synonym: (E)-2-Cyano-3-[5-(3-hydroxyphenyl)thiophen-2-yl]acrylamide
YTHDF2 inhibitor
Molekulargewicht: 270.31
Reinheit: >98% by TLC NMR (Conforms)
Formulierung: Yellow solid
CAS Nummer: [3069691-93-6]
Formel: C14H10N2O2S
Anwendungsbeschreibung: DC-Y13-27 is an inhibitor (IC50 = 21.8 µM) of the RNA N6-methyladenosine (m6A) reader YTHDF2.1 It significantly enhanced tumor growth inhibition in MC38 murine models in conjunction with radiotherapy and/or anti-PD-L1 therapy via an increase in the number of CD8+ T cells.