DC-Y13-27, CAS [[3069691-93-6]]

Product Overview

• Article Name: DC-Y13-27, CAS [[3069691-93-6]]
• Biozol Catalog Number: FBM-10-4884
• Supplier Catalog Number: 10-4884
• Alternative Catalog Number: FBM-10-4884-5MG, FBM-10-4884-25MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: Chemical Name: (E)-2-Cyano-3-[5-(3-hydroxyphenyl)thiophen-2-yl]prop-2-enamide. Alternate Names: (E)-2-Cyano-3-[5-(3-hydroxyphenyl)thiophen-2-yl]acrylamide

Product Description

YTHDF2 inhibitor

Product Properties

• Molecular Weight: 270.31
• Purity: >98% by TLC NMR (Conforms)
• Form: Yellow solid
• CAS Number: [3069691-93-6]
• Formula: C14H10N2O2S

Application Notes

• Application Notes: DC-Y13-27 is an inhibitor (IC50 = 21.8 µM) of the RNA N6-methyladenosine (m6A) reader YTHDF2.1 It significantly enhanced tumor growth inhibition in MC38 murine models in conjunction with radiotherapy and/or anti-PD-L1 therapy via an increase in the number of CD8+ T cells.