DHP-103, CAS [[2775311-82-3]]

Produktübersicht

• Artikelname: DHP-103, CAS [[2775311-82-3]]
• Artikelnummer: FBM-10-4906
• Hersteller Artikelnummer: 10-4906
• Alternativnummer: FBM-10-4906-5MG,FBM-10-4906-25MG
• Hersteller: Focus Biomolecules
• Kategorie: Biochemikalien

Produktbeschreibung

Selective KCa3.1 blocker

Produkteigenschaften

• Molekulargewicht: 359.28
• Reinheit: >98% by HPLC NMR (Conforms)
• Formulierung: Yellow solid
• CAS Nummer: [2775311-82-3]
• Formel: C16H13F4NO4

Anwendungsbeschreibung

• Anwendungsbeschreibung: DHP-103 is a potent (IC50 = 6 nM) blocker of the intermediate-conductance calcium-activated potassium channel KCa3.1. It displays exquisite selectivity over calcium channels. It blocked mutant KCa3.1 channels that cause hereditary xerocytosis and reduced infarct volume, improved balance beam performance, and reduced activated microglia in a rat model of acute ischemic stroke.