DHP-103, CAS [[2775311-82-3]]

Product Overview

• Article Name: DHP-103, CAS [[2775311-82-3]]
• Biozol Catalog Number: FBM-10-4906
• Supplier Catalog Number: 10-4906
• Alternative Catalog Number: FBM-10-4906-5MG, FBM-10-4906-25MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: Chemical Name: Dimethyl 4-(4-Fluoro-3-(trifluoromethyl)phenyl-1,4-dihydropyridine-3,5-dicarboxylate

Product Description

Selective KCa3.1 blocker

Product Properties

• Molecular Weight: 359.28
• Purity: >98% by HPLC NMR (Conforms)
• Form: Yellow solid
• CAS Number: [2775311-82-3]
• Formula: C16H13F4NO4

Application Notes

• Application Notes: DHP-103 is a potent (IC50 = 6 nM) blocker of the intermediate-conductance calcium-activated potassium channel KCa3.1. It displays exquisite selectivity over calcium channels. It blocked mutant KCa3.1 channels that cause hereditary xerocytosis and reduced infarct volume, improved balance beam performance, and reduced activated microglia in a rat model of acute ischemic stroke.