TJ-M2010-5, CAS [[1357471-57-8]]

Produktübersicht

• Artikelname: TJ-M2010-5, CAS [[1357471-57-8]]
• Artikelnummer: FBM-10-4919
• Hersteller Artikelnummer: 10-4919
• Alternativnummer: FBM-10-4919-5MG, FBM-10-4919-25MG
• Hersteller: Focus Biomolecules
• Kategorie: Biochemikalien
• Alternative Synonym: Chemical Name: 3-(4-Benzylpiperazin-1-yl)-N-(4-phenyl-1,3-thiazol-2-yl)propanamide

Produktbeschreibung

MyD88 inhibitor

Produkteigenschaften

• Molekulargewicht: 406.55
• Reinheit: >98% by HPLC NMR (Conforms)
• Formulierung: White solid
• CAS Nummer: [1357471-57-8]
• Formel: C23H26N4OS

Anwendungsbeschreibung

• Anwendungsbeschreibung: TJ-M2010-5 is an inhibitor of the toll-like receptor(TLR)/adaptor molecule myeloid differentiation factor 88 (MyD88) signaling pathway, crucial for inflammation and associated with the development of many inflammation-related cancers.1 It ameliorates ischemia-reperfusion injury in various organ models including brain2, liver3, and heart4. TJ-M2010-5 also suppressed proliferation, migration, and invasion in MCF-7 and MDA-MB-231 breast cancer cells.5 It prevented colitis-associated colorectal cancer by impairing myeloid-derived suppressor cells.6