TJ-M2010-5, CAS [[1357471-57-8]]

Product Overview

• Article Name: TJ-M2010-5, CAS [[1357471-57-8]]
• Biozol Catalog Number: FBM-10-4919
• Supplier Catalog Number: 10-4919
• Alternative Catalog Number: FBM-10-4919-5MG,FBM-10-4919-25MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien

Product Description

MyD88 inhibitor

Product Properties

• Molecular Weight: 406.55
• Purity: >98% by HPLC NMR (Conforms)
• Form: White solid
• CAS Number: [1357471-57-8]
• Formula: C23H26N4OS

Application Notes

• Application Notes: TJ-M2010-5 is an inhibitor of the toll-like receptor(TLR)/adaptor molecule myeloid differentiation factor 88 (MyD88) signaling pathway, crucial for inflammation and associated with the development of many inflammation-related cancers.1 It ameliorates ischemia-reperfusion injury in various organ models including brain2, liver3, and heart4. TJ-M2010-5 also suppressed proliferation, migration, and invasion in MCF-7 and MDA-MB-231 breast cancer cells.5 It prevented colitis-associated colorectal cancer by impairing myeloid-derived suppressor cells.6