Asunaprevir, CAS [[630420-16-5]]

Produktübersicht

• Artikelname: Asunaprevir, CAS [[630420-16-5]]
• Artikelnummer: FBM-10-4928
• Hersteller Artikelnummer: 10-4928
• Alternativnummer: FBM-10-4928-5MG, FBM-10-4928-25MG
• Hersteller: Focus Biomolecules
• Kategorie: Biochemikalien
• Alternative Synonym: Chemical Name: tert-Butyl N-[(2S)-1-[(2S,4R)-4-(7-chloro-4-methoxyisoquinolin-1-yl)oxy-2-[[(1R,2S)-1-(cyclopropylsulfonylcarbamoyl)-2-ethenylcyclopropyl]carbamoyl]pyrrolidine-1-yl]-3,3-dimethyl-1-oxobutan-2-yl]carbamate

Produktbeschreibung

HCV NS3 protease inhibitor/CRISPR enhancer

Produkteigenschaften

• Molekulargewicht: 748.29
• Reinheit: >98% by HPLC NMR (Conforms)
• Formulierung: White solid
• CAS Nummer: [630420-16-5]
• Formel: C35H46ClN5O9S

Anwendungsbeschreibung

• Anwendungsbeschreibung: Asunaprevir is a potent hepatitis C virus NS3 protease inhibitor (IC50 = 0.2 - 3.5 nM).1 Asunaprevir was used as part of a repressible Cas9 system (small molecule-assisted shut off - SMASh) capable of degrading newly synthesized Cas9 protein rapidly to precisely control gene editing.2,3 The Asunapreivr/SMASh system has also been using to target endogenous PD-1 protein for proteasomal degradation.4