Asunaprevir, CAS [[630420-16-5]]

Product Overview

• Article Name: Asunaprevir, CAS [[630420-16-5]]
• Biozol Catalog Number: FBM-10-4928
• Supplier Catalog Number: 10-4928
• Alternative Catalog Number: FBM-10-4928-5MG, FBM-10-4928-25MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: Chemical Name: tert-Butyl N-[(2S)-1-[(2S,4R)-4-(7-chloro-4-methoxyisoquinolin-1-yl)oxy-2-[[(1R,2S)-1-(cyclopropylsulfonylcarbamoyl)-2-ethenylcyclopropyl]carbamoyl]pyrrolidine-1-yl]-3,3-dimethyl-1-oxobutan-2-yl]carbamate

Product Description

HCV NS3 protease inhibitor/CRISPR enhancer

Product Properties

• Molecular Weight: 748.29
• Purity: >98% by HPLC NMR (Conforms)
• Form: White solid
• CAS Number: [630420-16-5]
• Formula: C35H46ClN5O9S

Application Notes

• Application Notes: Asunaprevir is a potent hepatitis C virus NS3 protease inhibitor (IC50 = 0.2 - 3.5 nM).1 Asunaprevir was used as part of a repressible Cas9 system (small molecule-assisted shut off - SMASh) capable of degrading newly synthesized Cas9 protein rapidly to precisely control gene editing.2,3 The Asunapreivr/SMASh system has also been using to target endogenous PD-1 protein for proteasomal degradation.4