Velpatasvir, CAS [[1377049-84-7]]

Produktübersicht

• Artikelname: Velpatasvir, CAS [[1377049-84-7]]
• Artikelnummer: FBM-10-4931
• Hersteller Artikelnummer: 10-4931
• Alternativnummer: FBM-10-4931-10MG,FBM-10-4931-50MG
• Hersteller: Focus Biomolecules
• Kategorie: Biochemikalien
• Alternative Synonym: GS-5816

Produktbeschreibung

Hepatitis C protease inhibitor

Produkteigenschaften

• Molekulargewicht: 883.02
• Reinheit: 98% by HPLC NMR (Conforms)
• Formulierung: Pale yellow solid
• CAS Nummer: [1377049-84-7]
• Formel: C49H54N8O8

Anwendungsbeschreibung

• Anwendungsbeschreibung: Velpatasvir is an extremely potent pan-genotypic hepatitis C virus (HCV) NS5A inhibitor.1 It is a component of Epclusa and Vosevi, two clinically useful medications with 98% and 97%, respectively, cure rates for HCV. It displayed EC50s for GTs 1-4, 6a ranging from 6-16 pM, GT5a at 75 pM, and GT6e at 130 pM. Velpatasvir also displayed an excellent barrier to viral resistance. It has been shown in silico, that velpatasvir binds to the SARS-CoV-2 spike protein and may be a potential therapeutic.2