Velpatasvir, CAS [[1377049-84-7]]

Product Overview

• Article Name: Velpatasvir, CAS [[1377049-84-7]]
• Biozol Catalog Number: FBM-10-4931
• Supplier Catalog Number: 10-4931
• Alternative Catalog Number: FBM-10-4931-10MG, FBM-10-4931-50MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: Chemical Name: Methyl [(2S)-1-[(2S,5S)-2-[9-[2-[(2S,4S)-1-[(2R)-2-[(methoxycarbonyl)amino]-2-phenylacetyl]-4-(methoxymethyl)pyrrolidin-2-yl]-1H-imidazol-5-yl]-1,11-dihydroisochromeno[4,3:6,7]naphtho[1,2-d]imidazol-2-yl]-5-methylpyrrolidin-1-yl]-3-methyl-1-oxobutan-2-yl]carbamate. Alternate Names: GS-5816

Product Description

Hepatitis C protease inhibitor

Product Properties

• Molecular Weight: 883.02
• Purity: 98% by HPLC NMR (Conforms)
• Form: Pale yellow solid
• CAS Number: [1377049-84-7]
• Formula: C49H54N8O8

Application Notes

• Application Notes: Velpatasvir is an extremely potent pan-genotypic hepatitis C virus (HCV) NS5A inhibitor.1 It is a component of Epclusa and Vosevi, two clinically useful medications with 98% and 97%, respectively, cure rates for HCV. It displayed EC50s for GTs 1-4, 6a ranging from 6-16 pM, GT5a at 75 pM, and GT6e at 130 pM. Velpatasvir also displayed an excellent barrier to viral resistance. It has been shown in silico, that velpatasvir binds to the SARS-CoV-2 spike protein and may be a potential therapeutic.2