PAT-1251, CAS [[2098884-53-6]]

Produktübersicht

• Artikelname: PAT-1251, CAS [[2098884-53-6]]
• Artikelnummer: FBM-10-4976
• Hersteller Artikelnummer: 10-4976
• Alternativnummer: FBM-10-4976-5MG, FBM-10-4976-25MG
• Hersteller: Focus Biomolecules
• Kategorie: Biochemikalien
• Alternative Synonym: Chemical Name: (R,R)-trans-(3-((4-(Aminomethyl)-6-(trifluoromethyl)pyridine-2-yl)oxy)phenyl)(3-fluoro-4-hydroxypyrrolidin-1-yl)methanone hydrochloride. Alternate Names: Lenumlostat hydrochloride

Produktbeschreibung

LOXL2 inhibitor

Produkteigenschaften

• Molekulargewicht: 435.80
• Reinheit: >98% by HPLC (NMR Conforms)
• Formulierung: White solid
• CAS Nummer: [2098884-53-6]
• Formel: C18H17F3N3O3HCl

Anwendungsbeschreibung

• Anwendungsbeschreibung: PAT-1251 is a potent (IC50 = 710 nM) inhibitor of LOXL2, a copper-dependent amine oxidase that deaminates lysine and hydroxylysine residues in collagen and elastin. It displayed >400-fold selectivity over LOX as well as high selectivity against the related amine oxidases SSAO, DAO, and MAO-A/B. A potential new therapeutic for the treatment of fibrotic diseases.