PAT-1251, CAS [[2098884-53-6]]

Product Overview

• Article Name: PAT-1251, CAS [[2098884-53-6]]
• Biozol Catalog Number: FBM-10-4976
• Supplier Catalog Number: 10-4976
• Alternative Catalog Number: FBM-10-4976-5MG, FBM-10-4976-25MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: Chemical Name: (R,R)-trans-(3-((4-(Aminomethyl)-6-(trifluoromethyl)pyridine-2-yl)oxy)phenyl)(3-fluoro-4-hydroxypyrrolidin-1-yl)methanone hydrochloride. Alternate Names: Lenumlostat hydrochloride

Product Description

LOXL2 inhibitor

Product Properties

• Molecular Weight: 435.80
• Purity: >98% by HPLC (NMR Conforms)
• Form: White solid
• CAS Number: [2098884-53-6]
• Formula: C18H17F3N3O3HCl

Application Notes

• Application Notes: PAT-1251 is a potent (IC50 = 710 nM) inhibitor of LOXL2, a copper-dependent amine oxidase that deaminates lysine and hydroxylysine residues in collagen and elastin. It displayed >400-fold selectivity over LOX as well as high selectivity against the related amine oxidases SSAO, DAO, and MAO-A/B. A potential new therapeutic for the treatment of fibrotic diseases.