OTUDin3, CAS [[441290-65-9]]

Produktübersicht

• Artikelname: OTUDin3, CAS [[441290-65-9]]
• Artikelnummer: FBM-10-4981
• Hersteller Artikelnummer: 10-4981
• Alternativnummer: FBM-10-4981-5MG, FBM-10-4981-25MG
• Hersteller: Focus Biomolecules
• Kategorie: Biochemikalien
• Alternative Synonym: Chemical Name: N-[3-(1H-Benzimidazol-2-yl)phenyl]-4-[(3,4-dihydro-2(1H)-isoquinolinyl)sulfonyl]benzamide

Produktbeschreibung

OTUD3 inhibitor

Produkteigenschaften

• Molekulargewicht: 508.60
• Reinheit: >98% by HPLC (NMR Conforms)
• Formulierung: White or off-white solid
• CAS Nummer: [441290-65-9]
• Formel: C29H24N4O3S

Anwendungsbeschreibung

• Anwendungsbeschreibung: OTUDin3 (441290-65-9) is a potent inhibitor of the deubiquitinase OTUD3, a member of the ovarian tumor proteases which plays a key role in tumorigenesis, neurodegeneration, metabolism, and immunity. It inhibited non-small cell lung cancer growth, migration, and invasion via enhancing the ubiquitination and degradation of the anti-apoptotic protein GRP78. OTUDin3 inhibited lung cancer growth in an H1299 mouse xenograft model.