OTUDin3, CAS [[441290-65-9]]

Catalog Number: FBM-10-4981
Article Name: OTUDin3, CAS [[441290-65-9]]
Biozol Catalog Number: FBM-10-4981
Supplier Catalog Number: 10-4981
Alternative Catalog Number: FBM-10-4981-5MG, FBM-10-4981-25MG
Manufacturer: Focus Biomolecules
Category: Biochemikalien
Alternative Names: Chemical Name: N-[3-(1H-Benzimidazol-2-yl)phenyl]-4-[(3,4-dihydro-2(1H)-isoquinolinyl)sulfonyl]benzamide
OTUD3 inhibitor
Molecular Weight: 508.60
Purity: >98% by HPLC (NMR Conforms)
Form: White or off-white solid
CAS Number: [441290-65-9]
Formula: C29H24N4O3S
Application Notes: OTUDin3 (441290-65-9) is a potent inhibitor of the deubiquitinase OTUD3, a member of the ovarian tumor proteases which plays a key role in tumorigenesis, neurodegeneration, metabolism, and immunity. It inhibited non-small cell lung cancer growth, migration, and invasion via enhancing the ubiquitination and degradation of the anti-apoptotic protein GRP78. OTUDin3 inhibited lung cancer growth in an H1299 mouse xenograft model.