CID16020046, CAS [[834903-43-4]]

Produktübersicht

• Artikelname: CID16020046, CAS [[834903-43-4]]
• Artikelnummer: FBM-10-5362
• Hersteller Artikelnummer: 10-5362
• Alternativnummer: FBM-10-5362-5MG, FBM-10-5362-25MG
• Hersteller: Focus Biomolecules
• Kategorie: Biochemikalien
• Alternative Synonym: Chemical Name: 4-[4,6-Dihydro-4-(3-hydroxyphenyl)-3-(4-methylphenyl)-6-oxopyrrolo[3,4-c]pyrazol-5(1H)-yl]benzoic acid

Produktbeschreibung

GPR55 antagonist

Produkteigenschaften

• Molekulargewicht: 425.44
• Reinheit: >98% by HPLC NMR (Conforms)
• Formulierung: White to off-white solid
• CAS Nummer: [834903-43-4]
• Formel: C25H19N3O4

Anwendungsbeschreibung

• Anwendungsbeschreibung: CID16020046 is a selective GPR55 antagonist.1 In HEK293 cells expressing GPR55, the compound behaves as an antagonist on lysophosphatidylinositol (LPI)-mediated Ca2+ release but was inactive on cells expressing CB1 and CB2. It blocks LPI-induced migration of colon cancer cells.2 It displays protective effects against oxidized LDL-induced inflammation3, mitigates advanced glycation end products-induced chondrocyte activation4, and displays anti-inflammatory effects in various cells5,6. A useful tool for studying the role of GPR55 in cellular physiology.