CID16020046, CAS [[834903-43-4]]

Product Overview

• Article Name: CID16020046, CAS [[834903-43-4]]
• Biozol Catalog Number: FBM-10-5362
• Supplier Catalog Number: 10-5362
• Alternative Catalog Number: FBM-10-5362-5MG, FBM-10-5362-25MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: Chemical Name: 4-[4,6-Dihydro-4-(3-hydroxyphenyl)-3-(4-methylphenyl)-6-oxopyrrolo[3,4-c]pyrazol-5(1H)-yl]benzoic acid

Product Description

GPR55 antagonist

Product Properties

• Molecular Weight: 425.44
• Purity: >98% by HPLC NMR (Conforms)
• Form: White to off-white solid
• CAS Number: [834903-43-4]
• Formula: C25H19N3O4

Application Notes

• Application Notes: CID16020046 is a selective GPR55 antagonist.1 In HEK293 cells expressing GPR55, the compound behaves as an antagonist on lysophosphatidylinositol (LPI)-mediated Ca2+ release but was inactive on cells expressing CB1 and CB2. It blocks LPI-induced migration of colon cancer cells.2 It displays protective effects against oxidized LDL-induced inflammation3, mitigates advanced glycation end products-induced chondrocyte activation4, and displays anti-inflammatory effects in various cells5,6. A useful tool for studying the role of GPR55 in cellular physiology.