CID16020046, CAS [[834903-43-4]]

Catalog Number: FBM-10-5362
Article Name: CID16020046, CAS [[834903-43-4]]
Biozol Catalog Number: FBM-10-5362
Supplier Catalog Number: 10-5362
Alternative Catalog Number: FBM-10-5362-5MG,FBM-10-5362-25MG
Manufacturer: Focus Biomolecules
Category: Biochemikalien
GPR55 antagonist
Molecular Weight: 425.44
Purity: >98% by HPLC NMR (Conforms)
Form: White to off-white solid
CAS Number: [834903-43-4]
Formula: C25H19N3O4
Application Notes: CID16020046 is a selective GPR55 antagonist.1 In HEK293 cells expressing GPR55, the compound behaves as an antagonist on lysophosphatidylinositol (LPI)-mediated Ca2+ release but was inactive on cells expressing CB1 and CB2. It blocks LPI-induced migration of colon cancer cells.2 It displays protective effects against oxidized LDL-induced inflammation3, mitigates advanced glycation end products-induced chondrocyte activation4, and displays anti-inflammatory effects in various cells5,6. A useful tool for studying the role of GPR55 in cellular physiology.