Isohelenin, CAS [[470-17-7]]

Produktübersicht

• Artikelname: Isohelenin, CAS [[470-17-7]]
• Artikelnummer: FBM-10-5393
• Hersteller Artikelnummer: 10-5393
• Alternativnummer: FBM-10-5393-5MG, FBM-10-5393-25MG
• Hersteller: Focus Biomolecules
• Kategorie: Biochemikalien
• Alternative Synonym: Chemical Name: (3aR,8aR,9aR)-8a-methyl-3,5-dimethylenedecahydronaphtho[2,3-b]furan-2(3H)-one. Alternate Names: Isoalantolactone

Produktbeschreibung

NFkB inhibitor

Produkteigenschaften

• Molekulargewicht: 232.32
• Reinheit: 98% by TLC NMR (Conforms)
• Formulierung: White solid
• CAS Nummer: [470-17-7]
• Formel: C15H20O2

Anwendungsbeschreibung

• Anwendungsbeschreibung: A sesquiterpene lactone isolated from Mexican Indian medicinal plants known to have anti-inflammatory properties. A potent inhibitor of NFB (complete inhibition at 5 M)1 acting via inhibition of IKK6. Isohelenin-mediated NFB inhibition suppresses IL-8 expression2, iNOS expression3 and RANTES biosynthesis4. Displays protective effects in endotoxic shock in rodent models.5 Induces apoptosis in glioma cells.6