Isohelenin, CAS [[470-17-7]]

Product Overview

• Article Name: Isohelenin, CAS [[470-17-7]]
• Biozol Catalog Number: FBM-10-5393
• Supplier Catalog Number: 10-5393
• Alternative Catalog Number: FBM-10-5393-5MG, FBM-10-5393-25MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: Chemical Name: (3aR,8aR,9aR)-8a-methyl-3,5-dimethylenedecahydronaphtho[2,3-b]furan-2(3H)-one. Alternate Names: Isoalantolactone

Product Description

NFkB inhibitor

Product Properties

• Molecular Weight: 232.32
• Purity: 98% by TLC NMR (Conforms)
• Form: White solid
• CAS Number: [470-17-7]
• Formula: C15H20O2

Application Notes

• Application Notes: A sesquiterpene lactone isolated from Mexican Indian medicinal plants known to have anti-inflammatory properties. A potent inhibitor of NFB (complete inhibition at 5 M)1 acting via inhibition of IKK6. Isohelenin-mediated NFB inhibition suppresses IL-8 expression2, iNOS expression3 and RANTES biosynthesis4. Displays protective effects in endotoxic shock in rodent models.5 Induces apoptosis in glioma cells.6