Biotin-isoxazole, CAS [[1377605-22-5]]

Produktübersicht

• Artikelname: Biotin-isoxazole, CAS [[1377605-22-5]]
• Artikelnummer: FBM-10-5400
• Hersteller Artikelnummer: 10-5400
• Alternativnummer: FBM-10-5400-1MG, FBM-10-5400-5MG
• Hersteller: Focus Biomolecules
• Kategorie: Biochemikalien
• Alternative Synonym: Chemical Name: 6-(5-(Thiophen-2-yl)isoxazole-3-carboxamido)hexyl 5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanoate. Alternate Names: B-isox

Produktbeschreibung

Precipitates RNA Binding Proteins

Produkteigenschaften

• Molekulargewicht: 520.66
• Reinheit: 98% by TLC nMR (Conforms)
• Formulierung: Beige solid
• CAS Nummer: [1377605-22-5]
• Formel: C24H32N4O5S2

Anwendungsbeschreibung

• Anwendungsbeschreibung: Exposure of cell or tissue lysates to biotin-isoxazole precipitates hundreds of RNA-binding proteins with significant overlap to the constituents of RNA granules.1,2 In one study roughly 580 nuclear proteins were identified as being precipitated by B-Isox including TAF15, RNA polymerase II (largest subunit), numerous subunits of the mediator complex as well as a variety of enzymes involved in epigenetic modification of histones.3 SR domains were found to be the determinant that facilitates B-Isox precipitation.4 Also allows for the fractionation / isolation of SG-associated proteins and RNA precipitates.5