O151, CAS [[304478-23-7]]

Produktübersicht

• Artikelname: O151, CAS [[304478-23-7]]
• Artikelnummer: FBM-10-5933
• Hersteller Artikelnummer: 10-5933
• Alternativnummer: FBM-10-5933-5MG, FBM-10-5933-25MG
• Hersteller: Focus Biomolecules
• Kategorie: Biochemikalien
• Alternative Synonym: Chemical Name: 4-Bromo-N-cyclohexylidenebenzohydrazide

Produktbeschreibung

OGG1 inhibitor

Produkteigenschaften

• Molekulargewicht: 295.18
• Reinheit: >98% by HPLC NMR (Conforms)
• Formulierung: White solid
• CAS Nummer: [304478-23-7]
• Formel: C13H15BrN2O

Anwendungsbeschreibung

• Anwendungsbeschreibung: The DNA base excision repair (BER) pathway, which utilizes DNA glycosylases to initiate repair of specific DNA lesions, is the major pathway for the repair of DNA damage induced by oxidation, alkylation, and deamination.1 The BER pathway is now a validated target in cancer therapeutic development.2 O151 (2763063-26-7) is a selective and potent inhibitor of 8-oxoguanine DNA glycosylase-1 (OGG1) with IC50 of 0.6 µM.3