O151, CAS [[304478-23-7]]

Product Overview

• Article Name: O151, CAS [[304478-23-7]]
• Biozol Catalog Number: FBM-10-5933
• Supplier Catalog Number: 10-5933
• Alternative Catalog Number: FBM-10-5933-5MG, FBM-10-5933-25MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: Chemical Name: 4-Bromo-N-cyclohexylidenebenzohydrazide

Product Description

OGG1 inhibitor

Product Properties

• Molecular Weight: 295.18
• Purity: >98% by HPLC NMR (Conforms)
• Form: White solid
• CAS Number: [304478-23-7]
• Formula: C13H15BrN2O

Application Notes

• Application Notes: The DNA base excision repair (BER) pathway, which utilizes DNA glycosylases to initiate repair of specific DNA lesions, is the major pathway for the repair of DNA damage induced by oxidation, alkylation, and deamination.1 The BER pathway is now a validated target in cancer therapeutic development.2 O151 (2763063-26-7) is a selective and potent inhibitor of 8-oxoguanine DNA glycosylase-1 (OGG1) with IC50 of 0.6 µM.3