This gene encodes a cytokine that functions in inflammation and the maturation of B cells. In addition, the encoded protein has been shown to be an endogenous pyrogen capable of inducing fever in people with autoimmune diseases or infections. The protein
Reconstitute with 20mM Tris (pH8.0) and 150mM NaCl (pH8.0) to 0.1-1.0mg/ml. Do not vortex. Lyophilized from 20mM Tris (pH8.0), 150mM NaCl, 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose, ProClin 300.
Expression System:
HEK293 cells
Formulierung:
Lyophilized powder
Sequenz:
N-terminal His-Tag, Val30~Met212 (NP_000591.1)
Anwendungsbeschreibung:
Interleukin 6 (IL-6) is an interleukin that acts as both a pro-inflammatory cytokine and an anti-inflammatory myokine. Current data suggest that direct application of IL-6 on breast cancer cells inhibits proliferation in ER-positive (estrogen- receptor-
GTX00095-pro Functional Assay Image
The inhibition effect of GTX00095-pro Human IL6 protein (active) on cell proliferation. (A) Unstimulated MCF-7 cells cultured in serum-free DMEM for 96hrs. (B) MCF-7 cells cultured in serum-free DMEM, stimulated with 100 ng/ml IL-6 for 96hrs.
WB analysis of GTX00095-pro Human IL6 protein (active).
SDS-PAGE analysis of GTX00095-pro Human IL6 protein (active).
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