Human IL6 protein, His tag (active), Unconjugated

Catalog Number: GTX00095-PRO
Article Name: Human IL6 protein, His tag (active), Unconjugated
Biozol Catalog Number: GTX00095-PRO
Supplier Catalog Number: GTX00095-pro
Alternative Catalog Number: GTX00095-PRO-10
Manufacturer: GeneTex
Category: Proteine/Peptide
Application: FA
Species Reactivity: Human
Conjugation: Unconjugated
Alternative Names: interleukin 6 , BSF-2 , BSF2 , CDF , HGF , HSF , IFN-beta-2 , IFNB2 , IL-6
This gene encodes a cytokine that functions in inflammation and the maturation of B cells. In addition, the encoded protein has been shown to be an endogenous pyrogen capable of inducing fever in people with autoimmune diseases or infections. The protein
NCBI: 3569
UniProt: P05231
Buffer: Reconstitute with 20mM Tris (pH8.0) and 150mM NaCl (pH8.0) to 0.1-1.0mg/ml. Do not vortex. Lyophilized from 20mM Tris (pH8.0), 150mM NaCl, 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose, ProClin 300.
Expression System: HEK293 cells
Form: Lyophilized powder
Sequence: N-terminal His-Tag, Val30~Met212 (NP_000591.1)
Application Notes: Interleukin 6 (IL-6) is an interleukin that acts as both a pro-inflammatory cytokine and an anti-inflammatory myokine. Current data suggest that direct application of IL-6 on breast cancer cells inhibits proliferation in ER-positive (estrogen- receptor-
GTX00095-pro Functional Assay Image
The inhibition effect of GTX00095-pro Human IL6 protein (active) on cell proliferation.
(A) Unstimulated MCF-7 cells cultured in serum-free DMEM for 96hrs.
(B) MCF-7 cells cultured in serum-free DMEM, stimulated with 100 ng/ml IL-6 for 96hrs.
WB analysis of GTX00095-pro Human IL6 protein (active).
SDS-PAGE analysis of GTX00095-pro Human IL6 protein (active).