Human FNDC5 protein, His tag (active), Unconjugated

Artikelnummer: GTX00149-PRO
Artikelname: Human FNDC5 protein, His tag (active), Unconjugated
Artikelnummer: GTX00149-PRO
Hersteller Artikelnummer: GTX00149-pro
Alternativnummer: GTX00149-PRO-10
Hersteller: GeneTex
Kategorie: Proteine/Peptide
Applikation: FA
Spezies Reaktivität: Human
Konjugation: Unconjugated
Alternative Synonym: fibronectin type III domain containing 5 , FRCP2 , irisin
This gene encodes a secreted protein that is released from muscle cells during exercise. The encoded protein may participate in the development of brown fat. Translation of the precursor protein initiates at a non-AUG start codon at a position that is co
NCBI: 252995
UniProt: Q8NAU1
Puffer: Reconstitute with 20mM Tris (pH8.0) and 150mM NaCl (pH8.0) to 0.1-1.0mg/ml. Do not vortex. Lyophilized from 20mM Tris (pH8.0), 150mM NaCl, 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose, ProClin 300.
Expression System: E. coli
Formulierung: Lyophilized powder
Sequenz: N-terminal His-Tag, Leu2~Ile137 (NP_001165411.2)
Anwendungsbeschreibung: Fibronectin type III domain-containing protein 5, the precursor of irisin, is a protein that is encoded by the FNDC5 gene. It was reported that FNDC5 significantly decreased cell number, migration and viability through apoptosis in malignant MDA-MB-231 c
GTX00149-pro Functional Assay Image
SDS-PAGE analysis of GTX00149-pro Human FNDC5 protein (active).
Cell apoptosis effect of GTX00149-pro Human FNDC5 protein (active).
(A) Unstimulated MDA-MB-231 cells cultured in DMEM for 48hrs.
(B) MDA-MB-231 cells cultured in DMEM, stimulated with 4 nM FNDC5 for 48hrs.
WB analysis of GTX00149-pro Human FNDC5 protein (active).