Human FNDC5 protein, His tag (active), Unconjugated
Biozol Catalog Number:
GTX00149-PRO
Supplier Catalog Number:
GTX00149-pro
Alternative Catalog Number:
GTX00149-PRO-10
Manufacturer:
GeneTex
Category:
Proteine/Peptide
Application:
FA
Species Reactivity:
Human
Conjugation:
Unconjugated
Alternative Names:
fibronectin type III domain containing 5 , FRCP2 , irisin
This gene encodes a secreted protein that is released from muscle cells during exercise. The encoded protein may participate in the development of brown fat. Translation of the precursor protein initiates at a non-AUG start codon at a position that is co
Reconstitute with 20mM Tris (pH8.0) and 150mM NaCl (pH8.0) to 0.1-1.0mg/ml. Do not vortex. Lyophilized from 20mM Tris (pH8.0), 150mM NaCl, 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose, ProClin 300.
Expression System:
E. coli
Form:
Lyophilized powder
Sequence:
N-terminal His-Tag, Leu2~Ile137 (NP_001165411.2)
Application Notes:
Fibronectin type III domain-containing protein 5, the precursor of irisin, is a protein that is encoded by the FNDC5 gene. It was reported that FNDC5 significantly decreased cell number, migration and viability through apoptosis in malignant MDA-MB-231 c
GTX00149-pro Functional Assay Image
SDS-PAGE analysis of GTX00149-pro Human FNDC5 protein (active).
Cell apoptosis effect of GTX00149-pro Human FNDC5 protein (active). (A) Unstimulated MDA-MB-231 cells cultured in DMEM for 48hrs. (B) MDA-MB-231 cells cultured in DMEM, stimulated with 4 nM FNDC5 for 48hrs.
WB analysis of GTX00149-pro Human FNDC5 protein (active).
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