Mouse TNF alpha protein, His tag (active), Unconjugated

Artikelnummer: GTX00288-PRO
Artikelname: Mouse TNF alpha protein, His tag (active), Unconjugated
Artikelnummer: GTX00288-PRO
Hersteller Artikelnummer: GTX00288-pro
Alternativnummer: GTX00288-PRO-10
Hersteller: GeneTex
Kategorie: Proteine/Peptide
Applikation: FA
Spezies Reaktivität: Mouse
Konjugation: Unconjugated
Alternative Synonym: tumor necrosis factor , DIF , TNF-a , TNF-alpha , TNFSF2 , TNFalpha , Tnfa , Tnfsf1a , Tnlg1f
This gene encodes a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. Members of this family are classified based on primary sequence, function, and structure. This protein is synthesized as a type-II t
NCBI: 21926
UniProt: P06804
Puffer: Reconstitute with 20mM Tris (pH8.0) and 150mM NaCl (pH8.0) to 0.1-1.0mg/ml. Do not vortex. Lyophilized from 20mM Tris (pH8.0), 150mM NaCl, 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose, ProClin 300.
Expression System: HEK293 cells
Formulierung: Lyophilized powder
Sequenz: N-terminal His-Tag, Gly57~Leu235 (NP_001265530.1)
Anwendungsbeschreibung: TNF-a (Tumor necrosis factor), being an endogenous pyrogen, is able to induce fever, necrosis, inflammation and to inhibit tumorigenesis. As reported, TNF-a could inhibit the proliferation and induce necrosis of A549 cells, and the concentration of IL-1beta
GTX00288-pro Functional Assay Image
SDS-PAGE analysis of GTX00288-pro Mouse TNF alpha protein (active).
WB analysis of GTX00288-pro Mouse TNF alpha protein (active).
Cell necrosis effect of GTX00288-pro Mouse TNF alpha protein (active).
(A) Unstimulated A549 cells cultured in DMEM for 72hrs.
(B) A549 cells cultured in DMEM, stimulated with 10 ng/ml TNF alpha for 72hrs.