CD45 antibody [30-F11] (Biotin), IgG2b, Rat, Monoclonal
Artikelnummer:
GTX00456
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| Artikelname: | CD45 antibody [30-F11] (Biotin), IgG2b, Rat, Monoclonal |
| Artikelnummer: | GTX00456 |
| Hersteller Artikelnummer: | GTX00456 |
| Alternativnummer: | GTX00456-100 |
| Hersteller: | GeneTex |
| Wirt: | Rat |
| Kategorie: | Antikörper |
| Applikation: | FC |
| Spezies Reaktivität: | Mouse |
| Immunogen: | Mouse thymus or spleen |
| Konjugation: | Biotin |
| Alternative Synonym: | protein tyrosine phosphatase receptor type C , B220 , CD45 , CD45R , GP180 , L-CA , LCA , LY5 , T200 |
| The 30-F11 antibody reacts with mouse CD45, which is one of the most abundant hematopoietic markers and is expressed on all leukocytes (the Leukocyte Common Antigen, LCA). CD45 is a protein tyrosine phosphatase existing in several isoforms, each being generated and expressed in cell-specific patterns. With its broad cell distribution, CD45 is critical for many leukocyte functions, regulating signal transduction and cell activation associated with the T cell receptor, B cell receptor, and IL-2 receptor. Other forms of CD45, with restricted cellular expression, include CD45R (B220), CD45RA, CD45RB, CD45RO and others. |
| Klonalität: | Monoclonal |
| Konzentration: | 0.5 mg/ml (Please refer to the vial label for the specific concentration.) |
| Klon-Bezeichnung: | [30-F11] |
| Isotyp: | IgG2b |
| Sensitivitaet: | This antibody specifically reacts with all isoforms of CD45 and also with the alloantigens CD45.1 and CD45.2 (LCA). |
| NCBI: | 5788 |
| UniProt: | P08575 |
| Puffer: | 10mM NaH2PO4, 150mM NaCl, 0.09% Sodium azide. |
| Reinheit: | Purified by affinity chromatography |
| Formulierung: | Liquid |
