CD45 antibody [30-F11] (Biotin), IgG2b, Rat, Monoclonal

Catalog Number: GTX00456
Article Name: CD45 antibody [30-F11] (Biotin), IgG2b, Rat, Monoclonal
Biozol Catalog Number: GTX00456
Supplier Catalog Number: GTX00456
Alternative Catalog Number: GTX00456-100
Manufacturer: GeneTex
Host: Rat
Category: Antikörper
Application: FC
Species Reactivity: Mouse
Immunogen: Mouse thymus or spleen
Conjugation: Biotin
Alternative Names: protein tyrosine phosphatase receptor type C , B220 , CD45 , CD45R , GP180 , L-CA , LCA , LY5 , T200
The 30-F11 antibody reacts with mouse CD45, which is one of the most abundant hematopoietic markers and is expressed on all leukocytes (the Leukocyte Common Antigen, LCA). CD45 is a protein tyrosine phosphatase existing in several isoforms, each being generated and expressed in cell-specific patterns. With its broad cell distribution, CD45 is critical for many leukocyte functions, regulating signal transduction and cell activation associated with the T cell receptor, B cell receptor, and IL-2 receptor. Other forms of CD45, with restricted cellular expression, include CD45R (B220), CD45RA, CD45RB, CD45RO and others.
Clonality: Monoclonal
Concentration: 0.5 mg/ml (Please refer to the vial label for the specific concentration.)
Clone Designation: [30-F11]
Isotype: IgG2b
Sensitivity: This antibody specifically reacts with all isoforms of CD45 and also with the alloantigens CD45.1 and CD45.2 (LCA).
NCBI: 5788
UniProt: P08575
Buffer: 10mM NaH2PO4, 150mM NaCl, 0.09% Sodium azide.
Purity: Purified by affinity chromatography
Form: Liquid