CD40 antibody [FGK4.5/ FGK45] (APC), IgG2a, Rat, Monoclonal

Artikelnummer: GTX01483-07
Artikelname: CD40 antibody [FGK4.5/ FGK45] (APC), IgG2a, Rat, Monoclonal
Artikelnummer: GTX01483-07
Hersteller Artikelnummer: GTX01483-07
Alternativnummer: GTX01483-07-100
Hersteller: GeneTex
Wirt: Rat
Kategorie: Antikörper
Applikation: FC
Spezies Reaktivität: Mouse
Konjugation: APC
The FGK45 antibody reacts with mouse CD40, a 40-50 kDa glycoprotein member of the tumor necrosis factor receptor (TNFR) family. CD40 is constitutively expressed by antigen presenting cells, including dendritic cells, B cells, and macrophages. The interaction of CD40 and its ligand CD154, expressed on activated T cells, plays an essential role in mediating a broad range of immune and inflammatory responses including T cell dependent immunoglobulin class switching, germinal center formation, and the development of memory B cells. The FGK45 clone is reported to be functionally useful for both in vitro and in vivo activation of CD40 expressing antigen presenting cells. The FGK45 antibody reacts with mouse CD40, a 40-50 kDa glycoprotein member of the tumor necrosis factor receptor (TNFR) family.
Klonalität: Monoclonal
Konzentration: 0.2 mg/ml (Please refer to the vial label for the specific concentration.)
Klon-Bezeichnung: [FGK4.5/ FGK45]
Isotyp: IgG2a
NCBI: 21939
UniProt: P27512
Puffer: 10mM NaH2PO4, 150mM NaCl, 0.1% Gelatin, 0.09% Sodium azide.
Formulierung: Liquid
Anwendungsbeschreibung: *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.