CD40 antibody [FGK4.5/ FGK45] (APC), IgG2a, Rat, Monoclonal
Artikelnummer:
GTX01483-07
Hersteller Artikelnummer:
GTX01483-07
Alternativnummer:
GTX01483-07-100
Hersteller:
GeneTex
Wirt:
Rat
Kategorie:
Antikörper
Applikation:
FC
Spezies Reaktivität:
Mouse
Konjugation:
APC
The FGK45 antibody reacts with mouse CD40, a 40-50 kDa glycoprotein member of the tumor necrosis factor receptor (TNFR) family. CD40 is constitutively expressed by antigen presenting cells, including dendritic cells, B cells, and macrophages. The interaction of CD40 and its ligand CD154, expressed on activated T cells, plays an essential role in mediating a broad range of immune and inflammatory responses including T cell dependent immunoglobulin class switching, germinal center formation, and the development of memory B cells. The FGK45 clone is reported to be functionally useful for both in vitro and in vivo activation of CD40 expressing antigen presenting cells. The FGK45 antibody reacts with mouse CD40, a 40-50 kDa glycoprotein member of the tumor necrosis factor receptor (TNFR) family.
Klonalität:
Monoclonal
Konzentration:
0.2 mg/ml (Please refer to the vial label for the specific concentration.)