CD40 antibody [FGK4.5/ FGK45] (APC), IgG2a, Rat, Monoclonal

Catalog Number: GTX01483-07
Article Name: CD40 antibody [FGK4.5/ FGK45] (APC), IgG2a, Rat, Monoclonal
Biozol Catalog Number: GTX01483-07
Supplier Catalog Number: GTX01483-07
Alternative Catalog Number: GTX01483-07-100
Manufacturer: GeneTex
Host: Rat
Category: Antikörper
Application: FC
Species Reactivity: Mouse
Conjugation: APC
The FGK45 antibody reacts with mouse CD40, a 40-50 kDa glycoprotein member of the tumor necrosis factor receptor (TNFR) family. CD40 is constitutively expressed by antigen presenting cells, including dendritic cells, B cells, and macrophages. The interaction of CD40 and its ligand CD154, expressed on activated T cells, plays an essential role in mediating a broad range of immune and inflammatory responses including T cell dependent immunoglobulin class switching, germinal center formation, and the development of memory B cells. The FGK45 clone is reported to be functionally useful for both in vitro and in vivo activation of CD40 expressing antigen presenting cells. The FGK45 antibody reacts with mouse CD40, a 40-50 kDa glycoprotein member of the tumor necrosis factor receptor (TNFR) family.
Clonality: Monoclonal
Concentration: 0.2 mg/ml (Please refer to the vial label for the specific concentration.)
Clone Designation: [FGK4.5/ FGK45]
Isotype: IgG2a
NCBI: 21939
UniProt: P27512
Buffer: 10mM NaH2PO4, 150mM NaCl, 0.1% Gelatin, 0.09% Sodium azide.
Form: Liquid
Application Notes: *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.