PION antibody, Unconjugated, Rabbit, Polyclonal

Artikelnummer: GTX32001
Artikelname: PION antibody, Unconjugated, Rabbit, Polyclonal
Artikelnummer: GTX32001
Hersteller Artikelnummer: GTX32001
Alternativnummer: GTX32001-100
Hersteller: GeneTex
Wirt: Rabbit
Kategorie: Antikörper
Applikation: ELISA, IHC-P, WB
Spezies Reaktivität: Human, Mouse, Rat
Immunogen: PION antibody was raised against a 19 amino acid synthetic peptide near the carboxy terminus of human PION.The immunogen is located within amino acids 770 - 820 of PION.
Konjugation: Unconjugated
Alternative Synonym: gamma-secretase activating protein , PION
Accumulation of neurotoxic amyloid-beta is a major hallmark of Alzheimer disease (AD, MIM 104300). Formation of amyloid-beta is catalyzed by gamma-secretase (see PSEN1, MIM 104311), a protease with numerous substrates. PION, or GSAP, selectively increase
Klonalität: Polyclonal
Konzentration: 1 mg/ml (Please refer to the vial label for the specific concentration.)
Klon-Bezeichnung: Polyclonal
Molekulargewicht: 98
Isotyp: IgG
Sensitivitaet: Multiple isoforms of PION are known to exist. PION antibody is predicted to not cross-react with other F-box protein family members.
NCBI: 54103
UniProt: A4D1B5
Puffer: PBS, 0.02% Sodium azide.
Quelle: Human
Reinheit: Purified by antigen-affinity chromatography
Formulierung: Liquid
Anwendungsbeschreibung: WB: 0.25 µg/mL. IHC-P: 5 µg/mL. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
IHC-P analysis of mouse brain tissue using GTX32001 PION antibody.
Red : Primary antibody
Blue : DAPI
Dilution : 20 μg/ml
GTX32001 WB Image
IHC-P analysis of human brain tissue using GTX32001 PION antibody.
Working concentration : 20 μg/ml
IHC-P analysis of mouse brain tissue using GTX32001 PION antibody.
Working concentration : 5 μg/ml
IHC-P analysis of human brain tissue using GTX32001 PION antibody.
Working concentration : 5 μg/ml