PION antibody, Unconjugated, Rabbit, Polyclonal
Artikelnummer:
GTX32001
- Bilder (5)
Artikelname: | PION antibody, Unconjugated, Rabbit, Polyclonal |
Artikelnummer: | GTX32001 |
Hersteller Artikelnummer: | GTX32001 |
Alternativnummer: | GTX32001-100 |
Hersteller: | GeneTex |
Wirt: | Rabbit |
Kategorie: | Antikörper |
Applikation: | ELISA, IHC-P, WB |
Spezies Reaktivität: | Human, Mouse, Rat |
Immunogen: | PION antibody was raised against a 19 amino acid synthetic peptide near the carboxy terminus of human PION.The immunogen is located within amino acids 770 - 820 of PION. |
Konjugation: | Unconjugated |
Alternative Synonym: | gamma-secretase activating protein , PION |
Accumulation of neurotoxic amyloid-beta is a major hallmark of Alzheimer disease (AD, MIM 104300). Formation of amyloid-beta is catalyzed by gamma-secretase (see PSEN1, MIM 104311), a protease with numerous substrates. PION, or GSAP, selectively increase |
Klonalität: | Polyclonal |
Konzentration: | 1 mg/ml (Please refer to the vial label for the specific concentration.) |
Klon-Bezeichnung: | Polyclonal |
Molekulargewicht: | 98 |
Isotyp: | IgG |
Sensitivitaet: | Multiple isoforms of PION are known to exist. PION antibody is predicted to not cross-react with other F-box protein family members. |
NCBI: | 54103 |
UniProt: | A4D1B5 |
Puffer: | PBS, 0.02% Sodium azide. |
Quelle: | Human |
Reinheit: | Purified by antigen-affinity chromatography |
Formulierung: | Liquid |
Anwendungsbeschreibung: | WB: 0.25 µg/mL. IHC-P: 5 µg/mL. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications. |