PION antibody, Unconjugated, Rabbit, Polyclonal
Catalog Number:
GTX32001
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Article Name: | PION antibody, Unconjugated, Rabbit, Polyclonal |
Biozol Catalog Number: | GTX32001 |
Supplier Catalog Number: | GTX32001 |
Alternative Catalog Number: | GTX32001-100 |
Manufacturer: | GeneTex |
Host: | Rabbit |
Category: | Antikörper |
Application: | ELISA, IHC-P, WB |
Species Reactivity: | Human, Mouse, Rat |
Immunogen: | PION antibody was raised against a 19 amino acid synthetic peptide near the carboxy terminus of human PION.The immunogen is located within amino acids 770 - 820 of PION. |
Conjugation: | Unconjugated |
Alternative Names: | gamma-secretase activating protein , PION |
Accumulation of neurotoxic amyloid-beta is a major hallmark of Alzheimer disease (AD, MIM 104300). Formation of amyloid-beta is catalyzed by gamma-secretase (see PSEN1, MIM 104311), a protease with numerous substrates. PION, or GSAP, selectively increase |
Clonality: | Polyclonal |
Concentration: | 1 mg/ml (Please refer to the vial label for the specific concentration.) |
Clone Designation: | Polyclonal |
Molecular Weight: | 98 |
Isotype: | IgG |
Sensitivity: | Multiple isoforms of PION are known to exist. PION antibody is predicted to not cross-react with other F-box protein family members. |
NCBI: | 54103 |
UniProt: | A4D1B5 |
Buffer: | PBS, 0.02% Sodium azide. |
Source: | Human |
Purity: | Purified by antigen-affinity chromatography |
Form: | Liquid |
Application Notes: | WB: 0.25 µg/mL. IHC-P: 5 µg/mL. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications. |