Mre11 antibody [12D7], IgG1, Unconjugated, Mouse, Monoclonal

Produktübersicht

• Artikelname: Mre11 antibody [12D7], IgG1, Unconjugated, Mouse, Monoclonal
• Artikelnummer: GTX70212
• Hersteller Artikelnummer: GTX70212
• Alternativnummer: GTX70212-100
• Hersteller: GeneTex
• Wirt: Mouse
• Kategorie: Antikörper
• Applikation: ELISA, FA, ICC, IP, PLA, WB
• Spezies Reaktivität: Human
• Immunogen: Amino acids 182-582 of Mre11 expressed in E. coli.
• Konjugation: Unconjugated
• Alternative Synonym: MRE11 homolog, double strand break repair nuclease , ATLD , HNGS1 , MRE11A , MRE11B

Produktbeschreibung

MRE11 antibody recognizes MRE11 protein, an enzyme with a predicted molecular weight of ~81 kDa. MRE11 forms the core of the MRN (MRE11-RAD50-NBS1) complex, one of the first components of the DNA damage response (DDR) to DNA double-strand breaks where it recruits other signaling factors required for repair. MRE11 has both exonuclease and endonuclease activities, and is responsible for the DNA binding of the complex.

Produkteigenschaften

• Klonalität: Monoclonal
• Konzentration: 0.45 mg/ml (Please refer to the vial label for the specific concentration.)
• Klon-Bezeichnung: [12D7]
• Molekulargewicht: 81
• Isotyp: IgG1
• Sensitivitaet: We do not recommend use of this product for Mouse,Rat.
• NCBI: 4361
• UniProt: P49959
• Puffer: PBS, no preservative.
• Reinheit: Protein G purified
• Formulierung: Liquid

Anwendungsbeschreibung

• Anwendungsbeschreibung: WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.