Mre11 antibody [12D7], IgG1, Unconjugated, Mouse, Monoclonal
Catalog Number:
GTX70212
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| Article Name: | Mre11 antibody [12D7], IgG1, Unconjugated, Mouse, Monoclonal |
| Biozol Catalog Number: | GTX70212 |
| Supplier Catalog Number: | GTX70212 |
| Alternative Catalog Number: | GTX70212-100 |
| Manufacturer: | GeneTex |
| Host: | Mouse |
| Category: | Antikörper |
| Application: | ELISA, FA, ICC, IP, PLA, WB |
| Species Reactivity: | Human |
| Immunogen: | Amino acids 182-582 of Mre11 expressed in E. coli. |
| Conjugation: | Unconjugated |
| Alternative Names: | MRE11 homolog, double strand break repair nuclease , ATLD , HNGS1 , MRE11A , MRE11B |
| MRE11 antibody recognizes MRE11 protein, an enzyme with a predicted molecular weight of ~81 kDa. MRE11 forms the core of the MRN (MRE11-RAD50-NBS1) complex, one of the first components of the DNA damage response (DDR) to DNA double-strand breaks where it recruits other signaling factors required for repair. MRE11 has both exonuclease and endonuclease activities, and is responsible for the DNA binding of the complex. |
| Clonality: | Monoclonal |
| Concentration: | 0.45 mg/ml (Please refer to the vial label for the specific concentration.) |
| Clone Designation: | [12D7] |
| Molecular Weight: | 81 |
| Isotype: | IgG1 |
| Sensitivity: | We do not recommend use of this product for Mouse,Rat. |
| NCBI: | 4361 |
| UniProt: | P49959 |
| Buffer: | PBS, no preservative. |
| Purity: | Protein G purified |
| Form: | Liquid |
| Application Notes: | WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications. |
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