AM 251, CAS [[183232-66-8]]

Produktübersicht

• Artikelname: AM 251, CAS [[183232-66-8]]
• Artikelnummer: ISC-CB-010
• Hersteller Artikelnummer: CB-010
• Alternativnummer: ISC-CB-010
• Hersteller: Isca Biochemicals
• Kategorie: Biochemikalien

Produktbeschreibung

AM 251 is a potent CB1 receptor inverse agonist, with an IC50 of 8 nM at CB1 and 306-fold selectivity over CB2 receptors. AM 251 is also a GPR55 agonist with an EC50 of 39 nM and a µ-opioid receptor antagonist with a Ki of 251 nM. AM251 displays anorectic, antidepressant-like and analgesic effects in animals. AM251 can attenuate or reverse the nociceptive - hyperalgesia and allodynia - behaviours induced by burn injury.

Produkteigenschaften

• Molekulargewicht: 555.24
• Reinheit: 98% by TLC , NMR conforms
• Formulierung: Off-white solid
• Sequenz: N-(Piperidin-1-yl)-5-(4-iodophenyl)-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazole-3-carboxamide
• CAS Nummer: [183232-66-8]
• Formel: C22H21Cl2IN4O
• Target-Kategorie: µ Opioid receptors,Cannabinoid receptors

Anwendungsbeschreibung

• Anwendungsbeschreibung: ProductType: Small molecules